Genetic analyses of both vertebrates and invertebrates have been criticalto advancing our understanding of neural development. Large-scale mutagenesesin flies, worms and, more recently, zebrafish have ...
Cdc42 is a Rho-family GTPase that in yeast is important in establishing polarized bud growth. Here we show that Cdc42 is also essential in establishing and maintaining polarity in epithelial cells.
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