This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

The article provides a comprehensive review of the current progress and future prospects of high-pressure-driven chemical synthesis, offering constructive guidance for the design and development of ...

Chemistry is all around us. From the widespread production of global food supplies to the metabolism that fuels the tiniest of microorganisms, everything in our surroundings is produced and controlled ...

This chemical reaction enabled the environmentally-friendly and tailor-made synthesis of a broad scope of sulfonyl fluorides containing aromatic, aliphatic, and heterocyclic groups. The synthetic ...

A team of researchers from Yale University, U.S., successfully achieved the first stereoselective synthesis of the complex natural product (–)-gukulenin A (7), which exhibits notable cytotoxicity ...

IN THE COMPLEX WORLD of catalysis, solid catalysts stand out as especially complex. Compared with liquid-phase catalysts, which generally are discrete molecules with clearly defined structures, solid ...

Grinding stuff is probably one of the oldest ways to run a chemical reaction. For example, in the fourth century BCE, people extracted mercury from cinnabar by grinding the mineral with vinegar in ...

Every researcher knows the frustration: your groundbreaking experiment is on hold because the DNA sequence you need is "unmanufacturable". Or worse, after weeks of waiting, the oligos arrive with ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...